It is way easier that in previous versions of TFS, simply create a .tfignore file.

For example:

###################################### # Ignore .cpp files in the ProjA sub-folder and all its subfolders ProjA\*.cpp # # Ignore .txt files in this folder \*.txt # # Ignore .xml files in this folder and all its sub-folders *.xml # # Ignore all files in the Temp sub-folder \Temp # # Do not ignore .dll files in this folder nor in any of its sub-folders !*.dll